N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-prolinamide
1-Pyrrolidinecarboxylicacid, 2-(aminocarbonyl)-, 1,1-dimethylethyl ester, (2R)-
CAS: 70138-72-6
Molecular Formula: C10H18N2O3
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-prolinamide - Names and Identifiers
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-prolinamide - Physico-chemical Properties
| Molecular Formula | C10H18N2O3 |
| Molar Mass | 214.26 |
| Density | 1.155±0.06 g/cm3(Predicted) |
| Melting Point | 100-102 °C |
| Boling Point | 370.1±31.0 °C(Predicted) |
| Appearance | White powder |
| pKa | 15.97±0.20(Predicted) |
| Storage Condition | 2-8°C |
| MDL | MFCD03419274 |
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-D-prolinamide - Introduction
A chemical substance, 2-(aminocarbonyl, 1,1-dimethylethyl ester, 2R)- (, 2-(aminocarbonyl)-1,1-dimethylethyl ester, (2R)-), has the following properties:
Physical Properties:
-Appearance: Colorless liquid or solid
-Molecular formula: C10H19NO3
-Molecular weight: 201.26g/mol
-melting point: 68-70 ℃
-Boiling point: 107-109 ℃
-Solubility: Soluble in many common organic solvents such as ethanol, dimethylformamide and esters.
Chemical Properties:
, 2-(aminocarbonyl)-, 1,1-dimethylethyl ester, (2R)-is an amino acid protecting group, usually used in the synthesis of peptide chains. It has low chemical reactivity and is relatively stable to common acid-base conditions and oxidants. The Boc protecting group can be conveniently removed under appropriate conditions.
Use:
, 2-(aminocarbonyl)-, 1,1-dimethylethyl ester, (2R)-is commonly used in organic synthesis as a starting material for peptide synthesis and peptide chain elongation. It can be used to prepare polypeptides, peptide drugs and other related compounds by solid phase synthesis or liquid phase synthesis.
Preparation Method:
It can be obtained by the condensation reaction of D-prolinamide and Boc-iminomethylproline ester. This reaction will typically be carried out under basic conditions using a suitable activator (e. g., an organic acid chloride).
Safety Information:
When using, 2-(aminocarbonyl)-, 1,1-dimenthylethyl ester, (2R)-, you need to pay attention to the following safety matters:
-It is a chemical that is irritating to the eyes and skin. Wear protective glasses and gloves when using it.
-Avoid inhaling its dust or gas, and maintain good ventilation conditions during operation.
-store it in a dry, cool place, away from fire and combustibles.
-Check the integrity of the container regularly to avoid leakage or accidents.
-In case of contact or ingestion, seek medical advice immediately and show the package or other label to the doctor.
Physical Properties:
-Appearance: Colorless liquid or solid
-Molecular formula: C10H19NO3
-Molecular weight: 201.26g/mol
-melting point: 68-70 ℃
-Boiling point: 107-109 ℃
-Solubility: Soluble in many common organic solvents such as ethanol, dimethylformamide and esters.
Chemical Properties:
, 2-(aminocarbonyl)-, 1,1-dimethylethyl ester, (2R)-is an amino acid protecting group, usually used in the synthesis of peptide chains. It has low chemical reactivity and is relatively stable to common acid-base conditions and oxidants. The Boc protecting group can be conveniently removed under appropriate conditions.
Use:
, 2-(aminocarbonyl)-, 1,1-dimethylethyl ester, (2R)-is commonly used in organic synthesis as a starting material for peptide synthesis and peptide chain elongation. It can be used to prepare polypeptides, peptide drugs and other related compounds by solid phase synthesis or liquid phase synthesis.
Preparation Method:
It can be obtained by the condensation reaction of D-prolinamide and Boc-iminomethylproline ester. This reaction will typically be carried out under basic conditions using a suitable activator (e. g., an organic acid chloride).
Safety Information:
When using, 2-(aminocarbonyl)-, 1,1-dimenthylethyl ester, (2R)-, you need to pay attention to the following safety matters:
-It is a chemical that is irritating to the eyes and skin. Wear protective glasses and gloves when using it.
-Avoid inhaling its dust or gas, and maintain good ventilation conditions during operation.
-store it in a dry, cool place, away from fire and combustibles.
-Check the integrity of the container regularly to avoid leakage or accidents.
-In case of contact or ingestion, seek medical advice immediately and show the package or other label to the doctor.
Last Update：2024-04-09 19:05:51
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Product Name: D-1-N-Boc-Prolinamide Visit Supplier Webpage Request for quotation
CAS: 70138-72-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 70138-72-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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